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	Table of content
	1- Metabolism of poly(ADP-ribose) [including PARG] NAD metabolism signaling poly(ADP-ribosyl)ation poly ADP-ribose structure PARG conservation PARG sequences PARG gene bovine PARG 2- Poly ADP-ribose polymerase-1 : structure-function relationship • Poly (ADP-ribosyl)ation reactions automodification heteromodification • PARP-1 : gene, cDNA and protein mouse PARP-1 modular structure main features • PARP-1, a molecular nick-sensor nick sensor DNA loops DNA structures • The bi-partite NLS • The BRCT domain : an interface for protein-protein interaction BRCT domain • PARP-1 catalytic domain : the connection with ADP-ribosylating toxins catalytic domain donor site acceptor site gain-of-function • The partners of PARP-1 partners | Next |

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